2026-03151: Pioneer Hi-Bred International, Inc.: Availability of a Petition for a Determination of Nonregulated Status and Draft Plant Pest Risk Assessment for Insect Resistant and Herbicide-Tolerant DP-910521-2 Maize (Corn)
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We are advising the public that the Animal and Plant Health Inspection Service has received a petition from Pioneer Hi-Bred International, Inc. seeking a determination of nonregulated status for DP-910521-2 maize (corn) which has been developed using genetic engineering to express the Cry1B.34 protein for control of certain susceptible lepidopteran pests, the phosphinothricin acetyltransferase protein for tolerance to glufosinate-ammonium herbicides, and the phosphomannose isomerase protein used as a selectable marker. We are making the petition and draft plant pest risk assessment available for public review and comment.
The agency’s own summary, as published.
The rule, in full
927 words as published, February 18, 2026. View the original →
Federal Register, Volume 91 Issue 32 (Wednesday, February 18, 2026) [Federal Register Volume 91, Number 32 (Wednesday, February 18, 2026)] [Notices] [Pages 7422-7423] From the Federal Register Online via the Government Publishing Office [www.gpo.gov] [FR Doc No: 2026-03151] ----------------------------------------------------------------------- DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service [Docket No. APHIS-2025-1033] Pioneer Hi-Bred International, Inc.: Availability of a Petition for a Determination of Nonregulated Status and Draft Plant Pest Risk Assessment for Insect Resistant and Herbicide-Tolerant DP-910521-2 Maize (Corn)
Agency
Animal and Plant Health Inspection Service, USDA.
Action
Notice of availability. -----------------------------------------------------------------------
Summary
We are advising the public that the Animal and Plant Health Inspection Service has received a petition from Pioneer Hi-Bred International, Inc. seeking a determination of nonregulated status for DP-910521-2 maize (corn) which has been developed using genetic engineering to express the Cry1B.34 protein for control of certain susceptible lepidopteran pests, the phosphinothricin acetyltransferase protein for tolerance to glufosinate-ammonium herbicides, and the phosphomannose isomerase protein used as a selectable marker. We are making the petition and draft plant pest [[Page 7423]] risk assessment available for public review and comment.
Dates
We will consider all comments that we receive on or before April 20, 2026.
Addresses
You may submit comments by either of the following methods: Federal eRulemaking Portal: Go to www.regulations.gov. Enter APHIS-2025-1033 in the Search field. Select the Documents tab, then select the Comment button in the list of documents. Postal Mail/Commercial Delivery: Send your comment to Docket No. APHIS-2025-1033, Regulatory Analysis and Development, PPD, APHIS, 5601 Sunnyside Avenue #AP760, Beltsville, MD 20705. The petition, draft plant pest risk assessment, and any comments we receive on this docket may be viewed at www.regulations.gov, or in our reading room, which is located in 1620 of the USDA South Building, 14th Street and Independence Avenue SW, Washington, DC. Normal reading room hours are 8 a.m. to 4:30 p.m., Monday through Friday, except holidays. To be sure someone is there to help you, please call (202) 799-7039 before coming.
For Further Information Contact
Mr. Alan Pearson, Biotechnology Regulatory Services, APHIS, USDA, 5601 Sunnyside Avenue, AP100-3-WS- 1151, Beltsville, MD 20705; (301) 851-4061; email: [email protected].
Supplementary Information
Under the authority of the plant pest provisions of the Plant Protection Act (7 U.S.C. 7701 et seq.), the regulations in 7 CFR part 340, ``Introduction of Organisms and Products Altered or Produced Through Genetic Engineering Which Are Plant Pests or Which There Is Reason to Believe Are Plant Pests,'' regulate, among other things, the introduction (importation, interstate movement, or release into the environment) of organisms and products altered or produced through genetic engineering that are plant pests or that there is reason to believe are plant pests. Such organisms and products are considered ``regulated articles.'' Section 340.6(a) of the regulations provides that any person may submit a petition to the Animal and Plant Health Inspection Service (APHIS) seeking a determination that an article should not be regulated under 7 CFR part 340. Paragraphs (b) and (c) of Sec. 340.6 describe the form that a petition for a determination of nonregulated status must take and the information that must be included in the petition. APHIS has received a petition (APHIS Petition Number 25-197-01p) from Pioneer Hi-Bred International, Inc. seeking a determination of nonregulated status for DP-910521-2 maize (corn), designated as event DP910521, which has been developed using genetic engineering to express the Cry1B.34 protein for control of certain susceptible lepidopteran pests, the phosphinothricin acetyltransferase (PAT) protein for tolerance to glufosinate-ammonium herbicides, and the phosphomannose isomerase (PMI) protein used as a selectable marker. The petition states that the information provided indicates that DP910521 is unlikely to pose a plant pest risk and therefore should not be regulated under APHIS' regulations in 7 CFR part 340. As part of our decision-making process regarding the organism's regulatory status, APHIS prepared a draft plant pest risk assessment (PPRA) to assess the plant pest risk of the organism. APHIS' draft PPRA compared the pest risk posed by DP910521 with that of the nonmodified variety from which it was derived. The draft PPRA concluded that DP910521 is unlikely to pose an increased plant pest risk compared to the nonmodified corn. Paragraph (d) of Sec. 340.6 provides that APHIS will publish a notice in the Federal Register providing 60 days for public comment on petitions for a determination of nonregulated status. In accordance with Sec. 340.6(d), we are publishing this notice to inform the public that APHIS will accept written comments regarding the petition and draft PPRA from interested or affected persons for a period of 60 days from the date of this notice. The petition and draft PPRA are available for public review and comment, and copies are available as indicated under ADDRESSES and from the individual listed under the FOR FURTHER INFORMATION CONTACT section of this notice. We are particularly interested in receiving comments regarding biological or ecological issues, and we encourage the submission of scientific data, studies, or research to support your comments. After the comment period closes, APHIS will review and evaluate any information received during the comment period and any other relevant information. Based upon available information, APHIS will respond to the petitioner either approving or denying the petition. APHIS will post its regulatory determination on its website and publish a notice of availability in the Federal Register. Authority: 7 U.S.C. 7701-7772 and 7781-7786; 31 U.S.C. 9701; 7 CFR 2.22, 2.80, and 371.3. Done in Washington, DC, this 11th day of February 2026. Kelly Moore, Acting Administrator, Animal and Plant Health Inspection Service. [FR Doc. 2026-03151 Filed 2-17-26; 8:45 am] BILLING CODE 3410-34-P
Rulemaking docket
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Notice February 18, 2026Petition: Pioneer Hi-Bred International, Inc.; Determination of Nonregulated Status and Draft Plant Pest Risk Assessment for Insect Resistant and Herbicide-Tolerant DP-910521-2 Maize (Corn)
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Supporting & Related Material February 18, 2026Petition for the Determination of Nonregulated Status for Insect Resistant and Herbicide-Tolerant DP910521 Maize
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Supporting & Related Material February 18, 2026Pioneer Hi-Bred International, Inc. Petition for Determination of Nonregulated Status for Insect Resistant and Herbicide Resistant DP910521 Maize (Zea mays)
Public comments
What people are saying
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Anonymous Anonymous 2026-04-21
“PUBLIC COMMENT Docket No. APHIS-2025-1033 Re: Petition for Determination of Nonregulated Status, DP-910521-2 Maize (Pioneer Hi-Bred International, Inc.) This comment does not dispute that APHIS may conclude, on a sufficient evidentiary record, that DP910521 maize is unlikely to pose a greater plant pest risk than the nonmodified comparator. It addresses whether the published record identifies an adequate evidentiary basis for that conclusion with respect to four specific matters. I. Protein-Specific Evidentiary Basis for NTO Inference DP910521 maize expresses Cry1B.34, a chimeric insecticid...”
3,940 more characters
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Anonymous Anonymous 2026-04-21
“Yes”
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National Grain and Feed Association 2026-04-20
“See attached file(s)”
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Anonymous commenter 2026-03-30
Comment from BMNA = IBHF; ban modified nucleic acid = initiative ban hitler fascism
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National Corn Growers Association 2026-03-18
“See attached file(s)”
Read all comments on Regulations.gov →
Comment volume from Regulations.gov; the comment-submission API was retired in 2025, so comments are filed on Regulations.gov directly.
Documents
- Full text (Federal Register) · February 18, 2026
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