South Carolina 2025-2026 Regular Session Status: Enacted

H 4382 — Nonprescription Ephedrine Products

Last action — Effective date 05/19/26

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  1. ✓
    Introduced
  2. ✓
    In Committee
  3. ✓
    Passed House
  4. ✓
    Passed Senate
  5. ✓
    To Executive
  6. 6
    Enacted

This bill has been enacted into law. Introduced April 23, 2025. Enacted.

Signed by Governor Henry McMaster (Republican) on May 19, 2026.

Prognosis

Likely to advance 70% · moderate confidence

Where this bill stands today.

Odds of enactment

High

How often bills like it became law.

  • Enacted

    Current position in the legislative process.

  • 1 sponsor

    1 primary, 0 co-sponsors signed on.

  • Cleared a recorded vote

    Passed 3 recorded votes so far.

Prognosis reads this bill's own signals — stage, sponsorship breadth, committee status, recorded votes and cross-state momentum. Odds come from a model trained on which bills have become law.

In plain language

The bill requires manufacturers of ephedrine products to pay monthly data collection fees.

This legislation amends the law regarding the sale of products containing ephedrine, requiring manufacturers to pay monthly fees for data collection. It also establishes penalties for non-compliance by these manufacturers.

What this means for you
  • Small Business: Small businesses selling ephedrine products may face increased costs due to the new manufacturer fees.

Summary

AN ACT TO AMEND THE SOUTH CAROLINA CODE OF LAWS BY AMENDING SECTION 44-53-398, RELATING TO THE SALE OF PRODUCTS CONTAINING EPHEDRINE, PSEUDOEPHEDRINE, OR PHENYLPROPANOLAMINE, SO AS TO REQUIRE THAT MANUFACTURERS OF THESE PRODUCTS PAY MONTHLY FEES ASSOCIATED WITH DATA COLLECTION, TO ESTABLISH A PENALTY FOR MANUFACTURERS THAT FAIL TO COMPLY, AND FOR OTHER PURPOSES. - RATIFIED TITLE

Bill Text

What changed in the latest version

9 added · 77 removed

Plain-language change summary

The latest version of Bill H 4382 modifies how retailers handle the sale of products containing ephedrine or pseudoephedrine. One key change is that retailers are now required to electronically transmit certain information before completing a sale of these products. This update is important because it aims to enhance tracking and regulation of these items, which can be misused in illegal drug production, thereby improving public safety.

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Latest
02, 2026) - South Carolina Legislature Online South Carolina General Assembly126th Session, 2025-2026Bill 4382Indicates Matter StrickenIndicates New Matter(Text matches printed bills.
23, 2025) - South Carolina Legislature Online South Carolina General Assembly126th Session, 2025-2026Bill 4382Indicates Matter StrickenIndicates New Matter(Text matches printed bills.
Document has been reformatted to meet World Wide Web specifications.) Indicates Matter Stricken Indicates New Matter   Committee Report April 2, 2026   H.
Document has been reformatted to meet World Wide Web specifications.)                 A bill   TO AMEND THE SOUTH CAROLINA CODE OF LAWS BY AMENDING SECTION 44-53-398, RELATING TO THE SALE OF PRODUCTS CONTAINING EPHEDRINE OR PSEUDOEPHEDRINE;
4382   Introduced by Rep.
Sessions   S.
Printed 4/2/26--H.
Read the first time April 23, 2025   ________   The committee on House Labor, Commerce and Industry To whom was referred a Bill (H.
4382) to amend the South Carolina Code of Laws by amending Section 44-53-398, relating to the sale of products containing ephedrine or pseudoephedrine;
so as to require, etc., respectfully Report:
That they have duly and carefully considered the same, and recommend that the same do pass with amendment:
      Amend the bill, as and if amended, SECTION 1, by striking Section 44-53-398(D)(2) and inserting:
       (2) Before completing a sale of a product regulated by this section, the retailer electronically shall transmit the information entered in the log to a data collection system provided by the National Association of Drug Diversion Investigators, or a successor or similar entity administrator of the data collection system.
The system must collect this data in real time and generate a stop sale alert if the sale would result in a violation of subsection (B) or a federal quantity restriction, which must be assessed on the basis of sales or purchases made in any state to the extent that information is available in the data collection system.
If the retailer receives a stop sale alert, the retailer must not complete the sale unless the retailer, upon notifying the purchaser the sale cannot be completed, reasonably fears bodily harm if he denies the sale due to the stop sale alert.
A product regulated by this section may not be sold without being reported to the data collection system unless the system is experiencing temporary technical difficulties that prevent a retailer from reporting the information to the system, and in that case, the retailer shall enter the necessary information in a written log, which must subsequently be entered into the electronic log within three business days of each business day that the electronic log was not operational.
A retailer using a written log under these circumstances is immune from liability during the time the system is temporarily disabled.
Amend the bill further, SECTION 1, by striking Section 44-53-398(D)(4)(a) and (b) and inserting:
       (4)(a) Beginning October 1, 20252026, any manufacturer of nonprescription products containing ephedrine, pseudoephedrine, or phenylpropanolamine sold in or into the State must, on a monthly basis, pay fees to the administrator of the data collection system described in item (2).
           (b) The administrator of the data collection system described in item (2) is responsible for setting the fee levels required pursuant to subitem (a).
The administrator of the data collection system shall, on an annual basis, establish the fee levels required pursuant to subsection (D)(4)(a);
in setting such fees, the administrator of the data collection system is prohibited from increasing fees on a per-product, per-transaction basis on a year-over-year basis by an amount equal to or in excess of ten percent, unless the administrator of the data collection system can show that the increase is directly attributable to cost factors to the administrator of the data collection system, including costs for labor, services, or materials used to administer the data collection system.
Renumber sections to conform.
Amend title to conform.
  WILLIAM HERBKERSMAN for Committee.
  _______                 A bill   TO AMEND THE SOUTH CAROLINA CODE OF LAWS BY AMENDING SECTION 44-53-398, RELATING TO THE SALE OF PRODUCTS CONTAINING EPHEDRINE OR PSEUDOEPHEDRINE;
----XX---- This web page was last updated on April 02, 2026 at 04:17 PM
----XX---- This web page was last updated on April 23, 2025 at 01:53 PM
View plain text versions (8)

Action History

  1. Effective date 05/19/26

  2. Act No. 235

  3. Signed By Governor

  4. Ratified R 248

  5. Roll call Yeas-111 Nays-0

  6. Concurred in Senate amendment and enrolled

  7. Scrivener's error corrected

  8. Read third time and returned to House with amendments

  9. Scrivener's error corrected

  10. Roll call Ayes-46 Nays-0

  11. Read second time

  12. Amended

  13. Committee report: Favorable Medical Affairs

  14. Referred to Committee on Medical Affairs

  15. Introduced and read first time

  16. Read third time and sent to Senate

  17. Roll call Yeas-112 Nays-0

  18. Read second time

  19. Amended

  20. Debate adjourned

  21. Requests for debate-Rep(s). Frank, Edgerton, Pace, Beach, Harris, Gilreath, Cromer, Terribile

  22. Committee report: Favorable with amendment Labor, Commerce and Industry

  23. Referred to Committee on Labor, Commerce and Industry

  24. Introduced and read first time

Sponsors

Sponsorship breakdown

Export CSV (upgrade) →

1 sponsors · 0 co-sponsors · 169 not signed on

Co-sponsors (0)

None.

Not signed on (169)

169 members have not signed on to this bill.

Show all 169 →

"Not signed on" means a member has not sponsored or co-sponsored this bill — it does not imply opposition. Members flagged Voted No have a recorded No vote on this bill.

Whip count is in markup. Polling the chamber and every recorded vote this session. Only the first open is slow. It’s instant for you after this. Calling the roll · Tallying · Engrossing

Votes

Passed 111 Yea · 0 Nay · 13 Other
Party YeaNayPresentNot Voting
Unaffiliated 1060013
Republican 2000
Democrat 2000
Total 1100013
% of votes cast 89%0%0%11%
How each member voted (123)
Member Party Vote
Brittain, T. Case, Jr. — Yea
Representative Luke S. Rankin — Yea
Henderson-Myers, Rosalyn D. — Yea
Johnson, Jeffrey E. — Yea
Johnson, Jermaine L., Sr. — Not Voting
Representative Adam L. Duncan — Yea
Representative Annie E. McDaniel — Yea
Representative April Cromer — Yea
Representative Beth E. Bernstein — Not Voting
Representative Bill Taylor — Yea
Representative Brandon Guffey — Yea
Representative Brandon L. Cox — Yea
Representative Brandon Newton — Yea
Representative Bruce W. Bannister — Yea
Representative Cally R. "Cal" Forrest, Jr. — Yea
Representative Carl L. Anderson — Yea
Representative Chandra E. Dillard — Yea
Representative Charles V. Hartz — Yea
Representative Chris Wooten — Yea
Representative Christopher R. "Chris" Hart — Yea
Representative Cody T. Mitchell — Yea
Representative Courtney S. Waters — Yea
Representative Craig A. Gagnon — Yea
Representative Daniel Gibson — Not Voting
Representative David Martin — Yea
Representative David R. Hiott — Yea
Representative David Vaughan — Yea
Representative Dennis C. Moss — Yea
Representative Dianne Mitchell — Yea
Representative Donald G. "Don" Chapman — Yea
Representative Donald Ryan McCabe, Jr. — Yea
Representative Elizabeth "Spencer" Wetmore — Yea
Representative Fawn M. Pedalino — Yea
Representative Gary S. Brewer, Jr. — Not Voting
Representative Gil Gatch — Yea
Representative Gilda Cobb-Hunter — Yea
Representative Greg Ford — Yea
Representative Hamilton R. Grant — Yea
Representative Harriet A. Holman — Yea
Representative Heath Sessions — Yea
Representative Heather Ammons Crawford — Yea
Representative Heather Bauer — Yea
Representative J. David Weeks — Not Voting
Representative J. Todd Rutherford — Yea
Representative JA Moore — Not Voting
Representative Jackie E. "Coach" Hayes — Yea
Representative Jackie R. Terribile — Yea
Representative James E. Teeple — Yea
Representative James Mikell "Mike" Burns — Not Voting
Representative Jeff Bradley — Yea
Representative Jerry N. Govan, Jr. — Not Voting
Representative John Gregory "Jay" Kilmartin — Yea
Representative John R. McCravy III — Yea
Representative John Richard C. King — Yea
Representative John T. Lastinger, Jr. — Yea
Representative Jordan S. Pace — Yea
Representative Joseph M. "Joe" Bustos — Not Voting
Representative Joseph S. "Joe" White — Not Voting
Representative Josiah Magnuson — Yea
Representative Justin T. Bamberg — Yea
Representative Kambrell H. Garvin — Yea
Representative Kathy Landing — Yea
Representative Keishan M. Scott — Yea
Representative Kevin Hardee — Yea
Representative Lee Hewitt — Yea
Representative Leon D. "Doug" Gilliam — Yea
Representative Leon Howard — Not Voting
Representative Leonidas E. "Leon" Stavrinakis — Yea
Representative Lonnie Hosey — Yea
Representative Lucas Atkinson — Yea
Representative M. Brian Lawson — Yea
Representative Mark N. Willis — Yea
Representative Melissa Lackey Oremus — Yea
Representative Micajah P. "Micah" Caskey IV — Yea
Representative Michael F. Rivers, Sr. — Yea
Representative Mike M. Neese — Yea
Representative Nathan Ballentine — Yea
Representative Neal A. Collins — Yea
Representative Patrick B. Haddon — Yea
Representative Paul B. Wickensimer — Yea
Representative Paula Rawl Calhoon — Yea
Representative Phillip Bowers — Yea
Representative Phillip D. Lowe — Yea
Representative Richard Blake Sanders — Yea
Representative Richard L. "Richie" Yow — Yea
Representative Robby Robbins — Yea
Representative Robert J. "Rob" Harris — Yea
Representative Robert Q. Williams — Yea
Representative Robert T. Reese — Yea
Representative Roger K. Kirby — Yea
Representative Sarita L. Edgerton — Yea
Representative Seth Rose — Yea
Representative Shannon S. Erickson — Yea
Representative Steven Wayne Long — Yea
Representative Sylleste H. Davis — Yea
Representative T. Alan Morgan, Jr. — Yea
Representative Terry Alexander — Yea
Representative Thomas Beach — Yea
Representative Thomas Duval "Val" Guest, Jr. — Yea
Representative Thomas E. "Tommy" Pope — Yea
Representative Thomas F. "Tom" Hartnett, Jr. — Yea
Representative Thomas Lee Gilreath — Yea
Representative Thomas R. "Randy" Ligon — Yea
Representative Timothy A. "Tim" McGinnis — Yea
Representative Travis A. Moore — Yea
Representative W. Scott Montgomery IV — Yea
Representative Wallace H. "Jay" Jordan, Jr. — Yea
Representative Wendell G. Gilliard — Not Voting
Representative Wendell K. Jones — Yea
Representative William "Bill" Clyburn — Yea
Representative William "Bill" Hager — Yea
Representative William C. "Chris" Huff — Yea
Representative William H. Bailey — Yea
Representative William M. "Bill" Chumley — Not Voting
Representative William M. "Bill" Hixon — Yea
Representative William R. "Bill" Whitmire — Yea
Representative Wm. Weston J. Newton — Yea
Smith, G. Murrell, Jr. — Yea
Smith, Marvin — Yea
Jason Luck Democrat Yea
Tiffany R. Spann-Wilder Democrat Yea
Carla M. Schuessler Republican Yea
Stephen D. Frank Republican Yea

Official roll call →

2nd Reading

Passed 46 Yea · 0 Nay
Party YeaNayPresentNot Voting
Unaffiliated 46000
Total 46000
% of votes cast 100%0%0%0%
How each member voted (46)

Official roll call →

Passage of Bill

Passed 112 Yea · 0 Nay · 12 Other
Party YeaNayPresentNot Voting
Unaffiliated 1090011
Republican 2000
Democrat 1001
Total 1120012
% of votes cast 90%0%0%10%
How each member voted (124)
Member Party Vote
Brittain, T. Case, Jr. — Yea
Representative Luke S. Rankin — Not Voting
Henderson-Myers, Rosalyn D. — Yea
Johnson, Jeffrey E. — Yea
Johnson, Jermaine L., Sr. — Yea
Representative Adam L. Duncan — Yea
Representative Annie E. McDaniel — Yea
Representative April Cromer — Yea
Representative Beth E. Bernstein — Yea
Representative Bill Taylor — Not Voting
Representative Brandon Guffey — Not Voting
Representative Brandon L. Cox — Yea
Representative Brandon Newton — Yea
Representative Bruce W. Bannister — Yea
Representative Cally R. "Cal" Forrest, Jr. — Yea
Representative Carl L. Anderson — Yea
Representative Chandra E. Dillard — Yea
Representative Charles V. Hartz — Not Voting
Representative Chris Wooten — Yea
Representative Christopher R. "Chris" Hart — Yea
Representative Cody T. Mitchell — Yea
Representative Courtney S. Waters — Yea
Representative Craig A. Gagnon — Yea
Representative Daniel Gibson — Yea
Representative David Martin — Yea
Representative David R. Hiott — Yea
Representative David Vaughan — Yea
Representative Dennis C. Moss — Not Voting
Representative Dianne Mitchell — Yea
Representative Donald G. "Don" Chapman — Yea
Representative Donald Ryan McCabe, Jr. — Yea
Representative Elizabeth "Spencer" Wetmore — Yea
Representative Fawn M. Pedalino — Yea
Representative Gary S. Brewer, Jr. — Yea
Representative Gil Gatch — Yea
Representative Gilda Cobb-Hunter — Yea
Representative Greg Ford — Yea
Representative Hamilton R. Grant — Yea
Representative Harriet A. Holman — Not Voting
Representative Heath Sessions — Yea
Representative Heather Ammons Crawford — Yea
Representative Heather Bauer — Yea
Representative J. David Weeks — Yea
Representative J. Todd Rutherford — Yea
Representative JA Moore — Yea
Representative Jackie E. "Coach" Hayes — Yea
Representative Jackie R. Terribile — Yea
Representative James E. Teeple — Yea
Representative James Mikell "Mike" Burns — Yea
Representative Jeff Bradley — Yea
Representative Jerry N. Govan, Jr. — Yea
Representative John Gregory "Jay" Kilmartin — Yea
Representative John R. McCravy III — Yea
Representative John Richard C. King — Not Voting
Representative John T. Lastinger, Jr. — Yea
Representative Jordan S. Pace — Yea
Representative Joseph M. "Joe" Bustos — Yea
Representative Joseph S. "Joe" White — Yea
Representative Josiah Magnuson — Yea
Representative Justin T. Bamberg — Yea
Representative Kambrell H. Garvin — Yea
Representative Kathy Landing — Yea
Representative Keishan M. Scott — Yea
Representative Kevin Hardee — Yea
Representative Lee Hewitt — Yea
Representative Leon D. "Doug" Gilliam — Yea
Representative Leon Howard — Not Voting
Representative Leonidas E. "Leon" Stavrinakis — Yea
Representative Lonnie Hosey — Yea
Representative Lucas Atkinson — Yea
Representative M. Brian Lawson — Yea
Representative Mark N. Willis — Yea
Representative Melissa Lackey Oremus — Yea
Representative Micajah P. "Micah" Caskey IV — Yea
Representative Michael F. Rivers, Sr. — Yea
Representative Mike M. Neese — Yea
Representative Nathan Ballentine — Yea
Representative Neal A. Collins — Yea
Representative Patrick B. Haddon — Yea
Representative Paul B. Wickensimer — Yea
Representative Paula Rawl Calhoon — Yea
Representative Phillip Bowers — Yea
Representative Phillip D. Lowe — Yea
Representative Richard Blake Sanders — Yea
Representative Richard L. "Richie" Yow — Yea
Representative Robby Robbins — Yea
Representative Robert J. "Rob" Harris — Yea
Representative Robert Q. Williams — Yea
Representative Robert T. Reese — Yea
Representative Roger K. Kirby — Yea
Representative Sarita L. Edgerton — Yea
Representative Seth Rose — Yea
Representative Shannon S. Erickson — Not Voting
Representative Steven Wayne Long — Yea
Representative Sylleste H. Davis — Yea
Representative T. Alan Morgan, Jr. — Yea
Representative Terry Alexander — Yea
Representative Thomas Beach — Yea
Representative Thomas Duval "Val" Guest, Jr. — Yea
Representative Thomas E. "Tommy" Pope — Yea
Representative Thomas F. "Tom" Hartnett, Jr. — Yea
Representative Thomas Lee Gilreath — Yea
Representative Thomas R. "Randy" Ligon — Yea
Representative Timothy A. "Tim" McGinnis — Yea
Representative Travis A. Moore — Yea
Representative W. Scott Montgomery IV — Not Voting
Representative Wallace H. "Jay" Jordan, Jr. — Yea
Representative Wendell G. Gilliard — Yea
Representative Wendell K. Jones — Yea
Representative William "Bill" Clyburn — Yea
Representative William "Bill" Hager — Yea
Representative William C. "Chris" Huff — Yea
Representative William G. "Bill" Herbkersman — Yea
Representative William H. Bailey — Yea
Representative William M. "Bill" Chumley — Yea
Representative William M. "Bill" Hixon — Yea
Representative William R. "Bill" Whitmire — Yea
Representative Wm. Weston J. Newton — Yea
Smith, G. Murrell, Jr. — Yea
Smith, Marvin — Not Voting
Jason Luck Democrat Yea
Tiffany R. Spann-Wilder Democrat Not Voting
Carla M. Schuessler Republican Yea
Stephen D. Frank Republican Yea

Official roll call →

Subjects

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Frequently asked questions

What does H 4382 do?
AN ACT TO AMEND THE SOUTH CAROLINA CODE OF LAWS BY AMENDING SECTION 44-53-398, RELATING TO THE SALE OF PRODUCTS CONTAINING EPHEDRINE, PSEUDOEPHEDRINE, OR PHENYLPROPANOLAMINE, SO AS TO REQUIRE THAT MANUFACTURERS OF THESE PRODUCTS PAY MONTHLY FEES ASSOCIATED WITH DATA COLLECTION, TO ESTABLISH A PENALTY FOR MANUFACTURERS THAT FAIL TO COMPLY, AND FOR OTHER PURPOSES. - RATIFIED TITLE
Who sponsors H 4382?
H 4382 is sponsored by Representative Heath Sessions.
What is the current status of H 4382?
This bill has been enacted into law. Introduced April 23, 2025. Enacted.
Where can I track H 4382?
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