Nonprescription Ephedrine Products
This legislation amends the law regarding the sale of products containing ephedrine, requiring manufacturers to pay monthly fees for data collection. It also establishes penalties for non-compliance by these manufacturers.
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H 4382 — Nonprescription Ephedrine Products
Last action — Effective date 05/19/26
No card. One bill, free forever — alerts when it moves.
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✓Introduced
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✓In Committee
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✓Passed House
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✓Passed Senate
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✓To Executive
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6Enacted
This bill has been enacted into law. Introduced April 23, 2025. Enacted.
Signed by Governor Henry McMaster (Republican) on May 19, 2026.
Prognosis
Where this bill stands today.
Odds of enactment
HighHow often bills like it became law.
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Enacted
Current position in the legislative process.
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1 sponsor
1 primary, 0 co-sponsors signed on.
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Cleared a recorded vote
Passed 3 recorded votes so far.
Prognosis reads this bill's own signals — stage, sponsorship breadth, committee status, recorded votes and cross-state momentum. Odds come from a model trained on which bills have become law.
In plain language
The bill requires manufacturers of ephedrine products to pay monthly data collection fees.
This legislation amends the law regarding the sale of products containing ephedrine, requiring manufacturers to pay monthly fees for data collection. It also establishes penalties for non-compliance by these manufacturers.
What this means for you
- Small Business: Small businesses selling ephedrine products may face increased costs due to the new manufacturer fees.
Summary
AN ACT TO AMEND THE SOUTH CAROLINA CODE OF LAWS BY AMENDING SECTION 44-53-398, RELATING TO THE SALE OF PRODUCTS CONTAINING EPHEDRINE, PSEUDOEPHEDRINE, OR PHENYLPROPANOLAMINE, SO AS TO REQUIRE THAT MANUFACTURERS OF THESE PRODUCTS PAY MONTHLY FEES ASSOCIATED WITH DATA COLLECTION, TO ESTABLISH A PENALTY FOR MANUFACTURERS THAT FAIL TO COMPLY, AND FOR OTHER PURPOSES. - RATIFIED TITLE
Bill Text
What changed in the latest version
9 added · 77 removedPlain-language change summary
The latest version of Bill H 4382 modifies how retailers handle the sale of products containing ephedrine or pseudoephedrine. One key change is that retailers are now required to electronically transmit certain information before completing a sale of these products. This update is important because it aims to enhance tracking and regulation of these items, which can be misused in illegal drug production, thereby improving public safety.
02,23, 2026)2025) - South Carolina Legislature Online South Carolina General Assembly126th Session, 2025-2026Bill 4382Indicates Matter StrickenIndicates New Matter(Text matches printed bills.
Document has been reformatted to meet World Wide Web specifications.) Indicates Matter Stricken Indicates New Matter Committee ReportA Aprilbill 2, 2026TO AMEND H.THE SOUTH CAROLINA CODE OF LAWS BY AMENDING SECTION 44-53-398, RELATING TO THE SALE OF PRODUCTS CONTAINING EPHEDRINE OR PSEUDOEPHEDRINE;
4382 Introduced by Rep.
Sessions S.
Printed 4/2/26--H.
Read the first time April 23, 2025 ________ The committee on House Labor, Commerce and Industry To whom was referred a Bill (H.
4382) to amend the South Carolina Code of Laws by amending Section 44-53-398, relating to the sale of products containing ephedrine or pseudoephedrine;
so as to require, etc., respectfully Report:
That they have duly and carefully considered the same, and recommend that the same do pass with amendment:
Amend the bill, as and if amended, SECTION 1, by striking Section 44-53-398(D)(2) and inserting:
(2) Before completing a sale of a product regulated by this section, the retailer electronically shall transmit the information entered in the log to a data collection system provided by the National Association of Drug Diversion Investigators, or a successor or similar entity administrator of the data collection system.
The system must collect this data in real time and generate a stop sale alert if the sale would result in a violation of subsection (B) or a federal quantity restriction, which must be assessed on the basis of sales or purchases made in any state to the extent that information is available in the data collection system.
If the retailer receives a stop sale alert, the retailer must not complete the sale unless the retailer, upon notifying the purchaser the sale cannot be completed, reasonably fears bodily harm if he denies the sale due to the stop sale alert.
A product regulated by this section may not be sold without being reported to the data collection system unless the system is experiencing temporary technical difficulties that prevent a retailer from reporting the information to the system, and in that case, the retailer shall enter the necessary information in a written log, which must subsequently be entered into the electronic log within three business days of each business day that the electronic log was not operational.
A retailer using a written log under these circumstances is immune from liability during the time the system is temporarily disabled.
Amend the bill further, SECTION 1, by striking Section 44-53-398(D)(4)(a) and (b) and inserting:
(4)(a) Beginning October 1, 20252026, any manufacturer of nonprescription products containing ephedrine, pseudoephedrine, or phenylpropanolamine sold in or into the State must, on a monthly basis, pay fees to the administrator of the data collection system described in item (2).
(b) The administrator of the data collection system described in item (2) is responsible for setting the fee levels required pursuant to subitem (a).
The administrator of the data collection system shall, on an annual basis, establish the fee levels required pursuant to subsection (D)(4)(a);
in setting such fees, the administrator of the data collection system is prohibited from increasing fees on a per-product, per-transaction basis on a year-over-year basis by an amount equal to or in excess of ten percent, unless the administrator of the data collection system can show that the increase is directly attributable to cost factors to the administrator of the data collection system, including costs for labor, services, or materials used to administer the data collection system.
Renumber sections to conform.
Amend title to conform.
WILLIAM HERBKERSMAN for Committee.
_______ A bill TO AMEND THE SOUTH CAROLINA CODE OF LAWS BY AMENDING SECTION 44-53-398, RELATING TO THE SALE OF PRODUCTS CONTAINING EPHEDRINE OR PSEUDOEPHEDRINE;
----XX---- This web page was last updated on April 02,23, 20262025 at 04:1701:53 PM
Action History
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Effective date 05/19/26
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Act No. 235
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Signed By Governor
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Ratified R 248
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Roll call Yeas-111 Nays-0
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Concurred in Senate amendment and enrolled
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Scrivener's error corrected
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Read third time and returned to House with amendments
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Scrivener's error corrected
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Roll call Ayes-46 Nays-0
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Read second time
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Amended
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Committee report: Favorable Medical Affairs
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Referred to Committee on Medical Affairs
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Introduced and read first time
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Read third time and sent to Senate
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Roll call Yeas-112 Nays-0
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Read second time
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Amended
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Debate adjourned
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Requests for debate-Rep(s). Frank, Edgerton, Pace, Beach, Harris, Gilreath, Cromer, Terribile
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Committee report: Favorable with amendment Labor, Commerce and Industry
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Referred to Committee on Labor, Commerce and Industry
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Introduced and read first time
Sponsors
- Representative Heath Sessions · Primary
Sponsorship breakdown
Export CSV (upgrade) →1 sponsors · 0 co-sponsors · 169 not signed on
Sponsors (1)
Co-sponsors (0)
None.
Not signed on (169)
169 members have not signed on to this bill.
Show all 169 →"Not signed on" means a member has not sponsored or co-sponsored this bill — it does not imply opposition. Members flagged Voted No have a recorded No vote on this bill.
Votes
| Party | Yea | Nay | Present | Not Voting |
|---|---|---|---|---|
| Unaffiliated | 106 | 0 | 0 | 13 |
| Republican | 2 | 0 | 0 | 0 |
| Democrat | 2 | 0 | 0 | 0 |
| Total | 110 | 0 | 0 | 13 |
| % of votes cast | 89% | 0% | 0% | 11% |
How each member voted (123)
| Party | Yea | Nay | Present | Not Voting |
|---|---|---|---|---|
| Unaffiliated | 46 | 0 | 0 | 0 |
| Total | 46 | 0 | 0 | 0 |
| % of votes cast | 100% | 0% | 0% | 0% |
How each member voted (46)
| Party | Yea | Nay | Present | Not Voting |
|---|---|---|---|---|
| Unaffiliated | 109 | 0 | 0 | 11 |
| Republican | 2 | 0 | 0 | 0 |
| Democrat | 1 | 0 | 0 | 1 |
| Total | 112 | 0 | 0 | 12 |
| % of votes cast | 90% | 0% | 0% | 10% |
How each member voted (124)
Subjects
Frequently asked questions
- What does H 4382 do?
- AN ACT TO AMEND THE SOUTH CAROLINA CODE OF LAWS BY AMENDING SECTION 44-53-398, RELATING TO THE SALE OF PRODUCTS CONTAINING EPHEDRINE, PSEUDOEPHEDRINE, OR PHENYLPROPANOLAMINE, SO AS TO REQUIRE THAT MANUFACTURERS OF THESE PRODUCTS PAY MONTHLY FEES ASSOCIATED WITH DATA COLLECTION, TO ESTABLISH A PENALTY FOR MANUFACTURERS THAT FAIL TO COMPLY, AND FOR OTHER PURPOSES. - RATIFIED TITLE
- Who sponsors H 4382?
- H 4382 is sponsored by Representative Heath Sessions.
- What is the current status of H 4382?
- This bill has been enacted into law. Introduced April 23, 2025. Enacted.
- Where can I track H 4382?
- Track H 4382 free on One Click Politics — get push/email alerts when it moves.
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